Après avoir aidé Dominic Toretto à échapper aux autorités, Brian O'Conner prépare ses affaires et quitte sa maison au volant de sa Mitsubishi 3000 GT modifiée. Peu de temps après, la police de Los Angeles arrive à sa maison, mais ils ne le trouvent pas. Un des officiers trouve l'insigne que Brian a laissé, révélant qu'il a démissionné...
A race-car driver whose career is on the skids because of his drinking falls for a rich society girl. That motivates him to clean up his act and resume his career, but it may be too late for that.
Billy Coy (Mickey Rooney) from Carrell in California wants to be a race car driver. He manages to get hired as a mechanic by Arthur "Red" Stanley (Thomas Mitchell) at his garage, after mentioning that he is the son of a famous driver called "Cannonball" Coy. Billy's father died in an accident at the Indianapolis 500 a few years ago.
Countess Diana Gaston (Patricia Roc) meets Vittorio Serra (Massimo Serato), the grandson of Carlo Serra, a prominent businessman. Convinced that she has met the man for her, she does all she can to keep him in her life. Unfortunately both of them are self-centered and this leads to repeated conflict. Vittorio's passion for auto racing leads to continued diagreements between him and the countess.
Lors d'un cambriolage en Italie, O'Donovan tire sur un gardien de nuit et un policier. Pour quitter le pays, il demande à Fraser, un conducteur de rallye, de le prendre comme coéquipier, moyennant rétribution.